Current work in the lab is focussed on cardiac arrhythmias, chrono-PGx and endometrial cancer. Below we include information on all our approved projects that are currently ongoing. An expert summary and a lay summary is provided for each project. For those projects approved by a board the relevant project code is provided
Current projects
- Unlocking Circadian Rhythms in Lynch Syndrome-associated cancer: Exploring Genetic Factors in Colorectal and Endometrial Cancer Development
- Identifying the link between the circadian clock and cardiac arrhythmia
- Is genetic chronotype linked to susceptibility to acute Covid-19 infection?
- Are mutations in UBR4 associated with Long QT syndrome or other cardiac arrhythmias in the 100K dataset?
- Investigating the impact of pathogenic non-coding variants in CYP21A2 on circadian steroidogenesis in congenital adrenal hyperplasia
- Enrichment analysis of associated disease and circadian genes in rheumatoid arthritis
- Identification and evaluation of chronopharmacogenomic (Chrono-PGx) variants
- Enhancing Diagnostic Equity of Genetic Testing Using Disease Super Panels
Chronomic Medicine Group 