Combining Genomic Medicine and Chronobiology
Department of Medical Genetics · University of Cambridge
About
The Chronomic Medicine group takes a comparative biology approach — spanning humans, zebrafish and plants — to investigate how chronobiology impacts human health and disease.
We coined the term "Chronomic Medicine" for the application of chronobiology to genomic medicine. With 52% of disease-causing genes predicted to oscillate across the day, there is vast unexplored potential for the clock in rare disease, variable phenotypes and therapeutic timing.
Our PI's lead involvement in the Cambridge Genomic Medicine Programme gives a unique opportunity to realise this. We take MPhil and MSt students each year and welcome clinical collaborators.
How circadian timing influences cardiac arrhythmias, Long QT syndrome and UBR4 pathways.
Circadian gene networks in Lynch Syndrome cancers, rheumatoid arthritis and adrenal hyperplasia.
Genetic variants that alter drug responses across the circadian cycle — time-aware precision medicine.
News
We welcome enquiries from prospective students, visiting scientists and clinical collaborators at all levels.
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