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Chronomic Medicine Group

Chronomic Medicine Group

Combining Genomic Medicine and Chronobiology

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  • AboutWhat is Chronomic Medicine?
  • ProjectsDiscover the current projects we are working on
  • Group MembersView previous and current lab members
  • Open ResearchFind data and software tools we have generated
  • NewsUpdates on group activities

Comparative Chronomics

Welcome to the Chronomic Medicine group website. We discover how circadian clocks contribute to genetic disease by taking a comparative biology approach. Take a look at our current projects below, find out about chronomic medicine or look through our data downloads.

About

The Chronomic Medicine group is based in the Department of Medical Genetics at the University of Cambridge and collaborates with colleagues across multiple departments. Our goal is to investigate how chronobiology impacts human health and disease. We are especially interested in the usage of chronobiology in genomic medicine; for which…Continue reading “About”

11Jul 2024

Identifying the link between the circadian clock and cardiac arrhythmia

Genomics England Research Registry ID: 431 Registered: 20/08/2020 Expert Summary The circadian clock is known to affect multiple aspects of health…

11Jul 2024
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Enrichment analysis of associated disease and circadian genes in rheumatoid arthritis

Genomics England Research Registry ID: 1090 Registered: 25/03/2024 Expert summary Rheumatoid arthritis (RA) is a chronic, systemic inflammatory autoimmune disease…

11Jul 202411 Jul 2024
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Showcasing the early women in genetics at Newnham College

This year Medical Genetics conference 2024 (ADMG24) was hosted at Newnham College on 1st July, and as part of the…

project

Investigating the impact of pathogenic non-coding variants in CYP21A2 on circadian steroidogenesis in congenital adrenal hyperplasia

11 Jul 202411 Jul 2024
Genomics England Research Registry ID: 1107 Registered: 08/05/2024 Expert Summary Congenital adrenal hyperplasia (CAH) refers to several disorders of biosynthesis of the steroid hormones cortisol and aldosterone. CAH is inherited in…
project

Identification and evaluation of chronopharmacogenomic (Chrono-PGx) variants

11 Jul 202411 Jul 2024
Genomics England Research Registry ID: 581 Registered: 30/04/2021 Expert Summary Existing approved drugs have complex pharmacological pathways that can be influenced by diurnal or seasonal regulation. This can guide future…
project

Enhancing Diagnostic Equity of Genetic Testing Using Disease Super Panels

11 Jul 202411 Jul 2024
Genomics England Research Registry ID: 1077 Registered: 07/03/2024 Expert summary This project aims to identify if Genomics England super panels provide better diagnostic power across ethnic groups than individual panels.…

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Find us here

The lab is based in the Department of Medical Genetics, located on level 6 of the Addenbrookes Treatment Centre.

Lab meetings are held in the School of Clinical Medicine.

Individual meetings are often held at Dr Hearn’s office in the Pightle at Newnham College

  • Newnham Walk, Cambridge, England
  • Addenbrookes Hospital, Hills Road, Cambridge CB2 0GG, England
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