Recent publications that members of Comparative Chronomics have been involved with:
Airoldi C, Hearn T, Brockington S, Webb AAR and Glover BJ (2019) TTG1 proteins regulate circadian activity as well as epidermal cell fate and pigmentation. Accepted at Nature Plants.
Fewings E, Ziemer M, Hörtnagel K, Reicherter K, Larionov A, Redman J, Goldgraben MA, Pepler A, Hearn T, Firth H, Ha T, Schaller J, Adams DJ, Rytina E, van Steensel M, Tischkowitz M. (2019) Malta (MYH9 Associated Elastin Aggregation) Syndrome: Germline Variants in MYH9 Cause Rare Sweat Duct Proliferations and Irregular Elastin Aggregations. Journal Investigative Dermatology. S0022-202X(19)31487-3.
Mombaerts L*, Carignano A*, Robertson FC*, Hearn TJ*, Junyang J, Hayden D, Rutterford Z, Hotta CT, Hubbard KE, Maria MRC, Yuan Y, Hannah MA, Goncalves J, Webb AAR. (2019) Dynamical differential expression (DyDE) reveals the period control mechanisms of the Arabidopsis circadian oscillator. PLoS Comput Biol. 15(1):e1006674.
Hearn TJ, Marti Ruiz MC, Abdul-Awal SM, Wimalasekera R, Stanton CR, Haydon MJ, Theodoulou FL, Hannah MA, Webb AAR. 2018. BIG Regulates Dynamic Adjustment of Circadian Period in Arabidopsis thaliana. Plant Physiol. 178(1):358-371. doi: 10.1104/pp.18.00571
Ohara T, Hearn TJ, Webb AAR, Satake A. 2018. Gene regulatory network models in response to sugars in the plant circadian system. J Theor Biol. 17;457:137-151. doi: 10.1016/j.jtbi.2018.08.020
Martí Ruiz MC, Hubbard KE, Gardner MJ, Jung HJ, Aubry S, Hotta CT, Mohd-Noh NI, Robertson FC, Hearn TJ, Tsai YC, Dodd AN, Hannah M, Carré IA, Davies JM, Braam J, Webb AAR. 2018. Circadian oscillations of cytosolic free calcium regulate the Arabidopsis circadian clock. Nat Plants. 4(9):690-698. doi: 10.1038/s41477-018-0224-8.
Frank A*, Matiolli CC*, Viana AJC*, Hearn TJ*, Kusakina J, Belbin FE, Wells Newman D, Yochikawa A, Cano-Ramirez DL, Chembath A, Cragg-Barber K, Haydon MJ, Hotta CT, Vincentz M, Webb AAR, Dodd AN. 2018. Circadian Entrainment in Arabidopsis by the Sugar-Responsive Transcription Factor bZIP63. Curr Biol. 28(16):2597-2606.e6. doi: 10.1016/j.cub.2018.05.092
Seki M, Ohara T, Hearn TJ, Frank A, da Silva VCH, Caldana C, Webb AAR, Satake A. (2017). Adjustment of the Arabidopsis circadian oscillator by sugar signalling dictates the regulation of starch metabolism. Scientific Reports. 7:8305.
Box MS, Domijan M, Huang BE, Jaeger KE, Khattak AK, Sedivy EL, Jones DM, Hearn TJ, Webb, AAR, Grant, A, Locke JCW and Wigge, PA. (2015). Natural variation in ELF3 controls thermoresponsive growth in Arabidopsis. Current Biology. 19. 194-9.
Hearn TJ and Webb AAR (2014). Measuring circadian oscillations of cytosolic-free calcium in Arabidopsis thaliana. Methods in Molecular Biology. 1158. 215-26.
*indicates equal contribution
See https://www.murrayedwards.cam.ac.uk/fellows/dr-timothy-hearn for past work
Comparative chronomics 